Intellectual Property Portfolio

Pat. UA162754 U, 23.04.2026. Method for obtaining N-(aryl or aralkyl)-pyrrole-2,5-dione derivatives exhibiting antifungal activity against Cryptococcus neoformans and Candida albicans. Tarnavskyi S.S., Lukashov S.S., Yarmoluk S.M., Bdzhola V.G., Demchenko A.M., Matiushok V.I.

Pat. UA160436 U, 10.09.2025. Method for obtaining an enzyme nanocomposite electrode based on graphene-containing textiles. Biloivan O.A., Tverdyi D.O., Korenchuk M.S., Lukashov S.S., Korpan Y.I.

Pat. UA145095 U, 25.11.2020. 1-Phenylpiperazine derivatives exhibiting antifungal activity against Cryptococcus neoformans. Protopopov M.V., Chekanov M.O., Syniugin A.R., Starosyla S.A., Volynets G.P., Bdzhola V.G., Yarmoluk S.M., Yarmoluk M.S., Matiushok V.I.

Pat. UA122373, 26.10.2020. Use of 5-(5-chloro-2-hydroxybenzylidene)-4-thioxothiazolidin-2-one as an MGMT inhibitor. Volynets G.P., Iatsyshyna A.P., Ruban T.P., Matsevych L.L., Nidoieva Z.M., Balanda A.O., Bdzhola V.G., Yarmoluk S.M., Lukash L.L.

Pat. UA144010 U, 25.08.2020. Application of small-molecular compound 2-amino-3-(1H-indol-3-yl)-N-phenylpropionamide hydrochloride as a compound with antibacterial activity against Acinetobacter baumannii. Volynets G.P., Chekanov M.O., Syniugin A.R., Bdzhola V.G., Starosyla S.A., Protopopov M.V., Yarmoluk S.M., Yarmoluk M.S., Matiushok V.I.

Pat. UA143105 U, 10.07.2020. Small-molecular antifungal compounds based on 6-chlorochromen-4-one. Volynets G.P., Sapelkin V.M., Bdzhola V.G., Starosyla S.A., Protopopov M.V., Yarmoluk S.M., Yarmoluk M.S., Matiushok V.I.

Pat. UA120678, 10.01.2020. Method for obtaining ajmaline. Kunakh V.A., Lukashov S.S., Mozhylevska L.P., Poronnik O.O., Yarmoluk S.M.

Pat. EP2507319 B1, 28.08.2019. Dyes for analysis of protein aggregation. Patton W.F., Dai L., Ludlam A., Yarmoluk S.M., Pande P., Kovalska V. et al.

Pat. UA127059 U, 10.07.2018. Method for identifying novel inhibitors of the repair enzyme O6-methylguanine-DNA methyltransferase for use in cancer chemotherapy. Volynets G.P., Ruban T.P., Iatsyshyna A.P., Matsevych L.L., Bdzhola V.G., Yarmoluk S.M., Lukash L.L.

Pat. CA2782045 C, 10.04.2018. Dyes for analysis of protein aggregation. Yarmoluk S.M., Pande P., Kovalska V., Volkova K., Coleman J., Losytskyy M., Balanda A., Shen D., Dai L., Ludlam A., Patton W.F.

Pat. US9932479 B2, 03.04.2018. Dyes and compositions, and processes for using same in analysis of protein aggregation and other applications. Patton W.F., Yarmoluk S.M., Pande P., Kovalska V., Dai L., Volkova K., Coleman J., Losytskyy M., Ludlam A., Balanda A.

Pat. UA123593 U, 26.02.2018. 2-(7-Furan-2-yl-2-morpholin-4-yl-4-oxo-4H-thiazolo[4,5-d]pyridazin-5-yl)-N-naphthalen-1-yl-acetamide exhibiting antitumor activity. Demchenko A.M., Yarmoluk S.M., Sharykina N.I., Bobkova L.S., Demchenko S.A., Kukharenko O.P.

Pat. UA117279 U, 26.06.2017. Novel small-molecular organic compounds with antituberculosis activity based on isonicotinic acid hydrazide. Volynets G.P., Tukalo M.A., Bdzhola V.G., Tarnavskyi S.S., Starosyla S.A., Gudzera O.Y., Yarmoluk S.M.

Pat. UA116134 U, 10.05.2017. Novel small-molecular organic compounds with antituberculosis activity based on benzaldehyde thiosemicarbazone. Volynets G.P., Tukalo M.A., Bdzhola V.G., Starosyla S.A., Tarnavskyi S.S., Gudzera O.Y., Kryklyvyi I.A., Yarmoluk S.M.

Certificate of Copyright Registration No. 69413, 26.12.2016. Computer program “PharmDeveloper”. Starosyla S.A., Volynets G.P., Bdzhola V.G., Yarmoluk S.M.

Pat. US9133343 B2, 15.09.2015. Dyes and compositions, and processes for using same in analysis of protein aggregation and other applications. Patton W.F., Yarmoluk S.M., Pande P., Kovalska V., Dai L., Volkova K., Coleman J., Losytskyy M., Ludlam A., Balanda A.

Pat. UA86041 U, 10.12.2013. Low-molecular organic ATP-competitive inhibitors of serine/threonine protein kinase CK2 based on the 4-aminothieno[2,3-d]pyrimidine heterocycle. Ostrynska O.V., Balanda A.O., Bdzhola V.G., Kotey I.M., Kukharenko O.P., Yarmoluk S.M.

Pat. WO2011/065980 (A2), 03.06.2011. Dyes for analysis of protein aggregation. Patton W.F., Yarmoluk S.M., Pande P., Kovalska V., Dai L., Volkova K., Coleman L., Losytskyy M., Ludlam A., Balanda A., Shen D.

Patent Application US2008091015 A1, 17.04.2008; WO 2008/027821 A1, 06.03.2008. Use of squaraine dyes to visualize protein during separations. Berkelman T.R., Yarmoluk S.M., Kovalska V.B., Losytskyy M.Yu., Volkova K.D.

Patent Application US2006207881, 21.09.2006. Detection of polyamino acids using trimethincyanine dyes. Kovalska V.B., Kryvorotenko D.V., Losytskyy M.Yu., Nording P., Rueck A., Schoenenberger B., Yarmoluk S.M., Wahl F.

Pat. UA4773, 15.02.2005. 5-[(4-Chlorophenyl)methylidene]-2-(4-oxyanilino)-4,5-dihydrothiazol-4-one exhibiting antitumor activity. Lesyk R.B., Zimenkovsky B.S., Yarmoluk S.M., Bdzhola V.G., Vovk O.I.

Pat. UA69165 A, 16.08.2004. Application of 4,5,6,7-tetrahalogeno-1,3-isoindolinediones as protein kinase CK2 inhibitors. Golub A.G., Yakovenko O.Ya., Yarmoluk S.M., Dubinina G.G., Bdzhola V.G., Prykhodko A.O.

Pat. UA68984 A, 16.08.2004. Application of 4-substituted 3-carboxyquinolines as protein kinase CK2 inhibitors. Sapelkin V.M., Lukashov S.S., Golub A.G., Bdzhola V.G., Yakovenko O.Ya., Yarmoluk S.M., Dubinina G.G.

Patent Application US2003175988, 18.09.2003. Method and compounds for the fluorescent labelling of biomolecules and polymer particles. Yarmoluk S.M., Kostenko O.M., Tolmachev O.I., Wolfbeis O.S.

Pat. UA61626 A, 19.03.2003. The structures with antitumor activity among 1-benzyl-3-chloro-4-anilino-2,5-dihydro-1H-2,5-pyrroledione derivatives. Tarnavsky S.S., Golovach S.M., Dubinina G.G., Yarmoluk S.M.