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Participation in the bioGENext Conference

Senior research scientist from the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, Galyna Volynets, participated in the...

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Participation in the Les Houches - TSRC - FEBS Workshop on Protein Dynamics

Senior research scientist from the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, Galyna Volynets, participated in the Les...

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Identification of novel antistaphylococcal hit compounds

Recently, the article dedicated to the development of novel antistaphylococcal agents targeting seryl-tRNA synthetase has been published.

Abstract:

Staphylococcus aureus is...

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Identification of dual-targeted Mycobacterium tuberculosis aminoacyl-tRNA synthetase inhibitors using machine learning

Recently, the article dedicated to the development of novel antituberculosis agents targeting aminoacyl-tRNA synthetases using machine learning approach has been...

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Our research:

FGFR1 Inhibitors
N-phenylnaphthostyril-1-sulfonamides Image
New class of FGFR1 kinase inhibitors with naphthostyril heterocycle has been...



 

ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1 Image
Virtual screening and biochemical screening allowed us to identify...



 

CK2 Inhibitors
2-aminopyrimidinones and their 6-aza-analogs Image
In order to find the new potent CK2 inhibitors 60 derivatives of...



 

Fluorescent Probes
Fluorescent detection of partially denatured conformation of beta-lactoglobuline Image
The native state of many proteins is known to be only marginally stable,...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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