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Benzaldehyde thiosemicarbazone derivatives against replicating and nonreplicating Mycobacterium tuberculosis

Recently, the article dedicated to the development of antituberculosis agents based on benzaldehyde thiosemicarbazone derivatives has been published.

Abstract:

In this article, we...

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Participation in FEBS 2018 Advanced Courses "Ligand-binding theory and practice"

Young scientist from the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, Galyna Volynets, participated in FEBS Advanced Course...

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Participation in the 43rd FEBS Congress

Young scientific researcher at the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, Maryna Kuperman, has attended the FEBS Congress "Biochemistry...

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Examining c-di-GMP and possible quorum sensing regulation in Pseudomonas fluorescens SBW25: links between intra- and inter-cellular regulation benefits community cooperative activities such as biofilm formation

Recently, the article dedicated to the investigation of possible role of bis-(3'-5')-cyclic dimeric  guanosine monophosphate (c-di-GMP) in quorum sensing regulation during biofilm...

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Our research:

CK2 Inhibitors
1,3-thiazole-5-carboxylic acid derivatives Image
Novel CK2 inhibitors among 1,3-thiazole-4-carboxylic acid derivatives have been...



 

ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1 Image
Virtual screening and biochemical screening allowed us to identify...



 

FGFR1 Inhibitors
Oxindoles Image
Oxindoles are known class of inhibitors of RTK, including FGFR1. We perform...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

Fluorescent Probes
Dyes for fluorescent detection of non-canonical DNA structures (triplexes and quadruplexes) Image
In living organisms genomic DNAs mostly exist in a double-stranded (ds) helical...



 

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