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Dual targeted hit identification using pharmacophore screening

Recently, the article dedicated to the development of dual-targeted inhibitors of mycobacterial aminoacyl-tRNA synthetases using pharmacophore screening has been...

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Dual-target inhibitors of mycobacterial aminoacyl-tRNA synthetases among N-benzylidene-N'-thiazol-2-yl-hydrazines

Recently, the article dedicated to the development of dual-targeted inhibitors of mycobacterial aminoacyl-tRNA synthetases among N-benzylidene-N'-thiazol-2-yl-hydrazines has been...

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Benzaldehyde thiosemicarbazone derivatives against replicating and nonreplicating Mycobacterium tuberculosis

Recently, the article dedicated to the development of antituberculosis agents based on benzaldehyde thiosemicarbazone derivatives has been published.

Abstract:

In this article, we...

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Participation in FEBS 2018 Advanced Courses "Ligand-binding theory and practice"

Young scientist from the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, Galyna Volynets, participated in FEBS Advanced Course...

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Our research:

ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1 Image
Virtual screening and biochemical screening allowed us to identify...



 

CK2 Inhibitors
1,3-thiazole-5-carboxylic acid derivatives Image
Novel CK2 inhibitors among 1,3-thiazole-4-carboxylic acid derivatives have been...



 

FGFR1 Inhibitors
N-phenylnaphthostyril-1-sulfonamides Image
New class of FGFR1 kinase inhibitors with naphthostyril heterocycle has been...



 

Fluorescent Probes
Long-wavelength dyes for fluorescent detection of proteins Image
Albumins are the major plasma proteins circulating in the bloodstream. Since...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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