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Dual targeted hit identification using pharmacophore screening

Recently, the article dedicated to the development of dual-targeted inhibitors of mycobacterial aminoacyl-tRNA synthetases using pharmacophore screening has been...

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Dual-target inhibitors of mycobacterial aminoacyl-tRNA synthetases among N-benzylidene-N'-thiazol-2-yl-hydrazines

Recently, the article dedicated to the development of dual-targeted inhibitors of mycobacterial aminoacyl-tRNA synthetases among N-benzylidene-N'-thiazol-2-yl-hydrazines has been...

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Benzaldehyde thiosemicarbazone derivatives against replicating and nonreplicating Mycobacterium tuberculosis

Recently, the article dedicated to the development of antituberculosis agents based on benzaldehyde thiosemicarbazone derivatives has been published.

Abstract:

In this article, we...

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Participation in FEBS 2018 Advanced Courses "Ligand-binding theory and practice"

Young scientist from the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, Galyna Volynets, participated in FEBS Advanced Course...

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Our research:

FGFR1 Inhibitors
Phenylbenzisoxazoles and aminopyrimidines Image
Phenylbenzisoxazoles and aminopyrimidines were also found from virtual...



 

ASK1 Inhibitors

 

CK2 Inhibitors
3-hydroxy-4'-carboxyflavone derivatives (FLC) Image
With the aim to identify new CK2 inhibitors virtual screening of 150,000 small...



 

Fluorescent Probes
Dyes for fluorescent detection of non-canonical DNA structures (triplexes and quadruplexes) Image
In living organisms genomic DNAs mostly exist in a double-stranded (ds) helical...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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