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Participation in the IX Young Scientists Conference, dedicated to the 160th anniversary of Kashchenko Mykola Feofanovych

PhD student at the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, Sergiy Starosyla, has attended the IX Young Scientists Conference, dedicated to...

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Design, synthesis and biological evaluation of N-phenylthieno[2,3-d]pyrimidin-4-amines as inhibitors of FGFR1

Our paper dedicated to the development of novel class of inhibitors for protein kinase FGFR1 has been published in Bioorganic and Medicinal Chemistry.  

Abstract: Fibroblast...

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Effect of inhibitors of protein kinase CK2 on the activity of its catalytic subunits СК2α and СК2α´

Our paper dedicated to the study of effect of inhibitors of protein kinase CK2 on the activity of its catalytic subunits CK2α and CK2α′ has been published in Biotechnologia Acta...

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Pharmacophore approaches in protein kinase inhibitors design

Our review, dedicated to the analysis of pharmacophore models for protein kinase inhibitors design has been published in World Journal of Pharmacology.

Abstract: Protein kinases...

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Our research:

FGFR1 Inhibitors
N-phenylnaphthostyril-1-sulfonamides Image
New class of FGFR1 kinase inhibitors with naphthostyril heterocycle has been...



 

CK2 Inhibitors
(thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids (TTP) Image
To study CK2 inhibitory activity of substituted (thieno[2,3-d]...



 

ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1 Image
Virtual screening and biochemical screening allowed us to identify...



 

Fluorescent Probes
Dyes for fluorescent detection of non-canonical DNA structures (triplexes and quadruplexes) Image
In living organisms genomic DNAs mostly exist in a double-stranded (ds) helical...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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