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Participation in the 2nd Conference for Young Scientists (CYS-2017)

Young scientists from the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, Svitlana Chernii and Maryna Kuperman, participated in...

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Development of the Algorithm for Pharmacophore Model Optimization and Rescoring of Pharmacophore Screening Results

Scientific researchers of the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, the NAS of Ukraine, have developed the algorithm for pharmacophore...

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Participation in the XXXI Scientific Conference on Bioorganic Chemistry and Petrochemistry

Scientific researchers of the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, the NAS of Ukraine, Synyugin A.R., Prykhod'ko A.O., Sapelkin V.M....

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Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1

Our manuscript dedicated to the development of novel inhibitors of protein kinase FGFR1 has been published in Bioorganic and Medicinal Chemistry. 

Abstract: 

Fibroblast growth...

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Our research:

CK2 Inhibitors
4-aminothieno[2,3-d]pyrimidines Image
Novel CK2 inhibitors among 4-aminothieno[2,3-d]pyrimidines have been...



 

FGFR1 Inhibitors
N-phenylnaphthostyril-1-sulfonamides Image
New class of FGFR1 kinase inhibitors with naphthostyril heterocycle has been...



 

ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1 Image
Virtual screening and biochemical screening allowed us to identify...



 

Fluorescent Probes
Fluorescent detection of partially denatured conformation of beta-lactoglobuline Image
The native state of many proteins is known to be only marginally stable,...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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