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Inhibitors of Protein Kinases 2012

On 24-27 August 2012 we participated in 7th International Conference "Inhibitors of Protein Kinases" (IPK'2012) that took place in Warsaw, Poland. Like previous Conferences in this...

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Electrochemical screening of the indole/quinolone derivatives as potential protein kinase CK2 inhibitors

We have published new scientific paper on CK2 inhibitors.

Abstract: An electrochemical method based on the bioorganometallic Fc-ATP cosubstrate for kinase-catalyzed phosphorylation...

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Structure-based discovery of novel flavonol inhibitors of human protein kinase CK2

We have published new scientific paper on CK2 inhibitors. 

Abstract: Serine/threonine protein kinase CK2 controls vast variety of fundamental processes in cell life; however...

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The new class of the human ASK1 inhibitors has been identified by our scientists

Apoptosis signal-regulating kinase 1 (ASK1) has recently emerged as an attractive therapeutic target for the treatment of cardiac and neurodegenerative disorders. The selective inhibitors...

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Our research:

ASK1 Inhibitors
Evaluation of 2-Thioxo-thiazolidin-4-ones Derivatives as Inhibitors of ASK1 Image
In order to discover novel ASK1 inhibitors we have performed screening program,...



 

CK2 Inhibitors
3-hydroxy-4'-carboxyflavone derivatives (FLC) Image
With the aim to identify new CK2 inhibitors virtual screening of 150,000 small...



 

FGFR1 Inhibitors
Quinazolines Image
Quinazolines is another known class of RTK inhibitors that is widely...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

Fluorescent Probes
Design of fluorescent dyes for biomedical applications Image
Search and development of novel highly efficient fluorescent probes for biology...



 

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