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Inhibitors of Protein Kinases 2012

On 24-27 August 2012 we participated in 7th International Conference "Inhibitors of Protein Kinases" (IPK'2012) that took place in Warsaw, Poland. Like previous Conferences in this...

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Electrochemical screening of the indole/quinolone derivatives as potential protein kinase CK2 inhibitors

We have published new scientific paper on CK2 inhibitors.

Abstract: An electrochemical method based on the bioorganometallic Fc-ATP cosubstrate for kinase-catalyzed phosphorylation...

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Structure-based discovery of novel flavonol inhibitors of human protein kinase CK2

We have published new scientific paper on CK2 inhibitors. 

Abstract: Serine/threonine protein kinase CK2 controls vast variety of fundamental processes in cell life; however...

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The new class of the human ASK1 inhibitors has been identified by our scientists

Apoptosis signal-regulating kinase 1 (ASK1) has recently emerged as an attractive therapeutic target for the treatment of cardiac and neurodegenerative disorders. The selective inhibitors...

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Our research:

FGFR1 Inhibitors
Oxindoles Image
Oxindoles are known class of inhibitors of RTK, including FGFR1. We perform...



 

ASK1 Inhibitors

 

CK2 Inhibitors
2-aminopyrimidinones and their 6-aza-analogs Image
In order to find the new potent CK2 inhibitors 60 derivatives of...



 

Fluorescent Probes
Design of fluorescent dyes for biomedical applications Image
Search and development of novel highly efficient fluorescent probes for biology...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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