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Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1

Our paper dedicated to the development of novel inhibitors of protein kinase FGFR1 has been published in Bioorganic and Medicinal Chemistry. 

Abstract: 

Fibroblast growth...

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Contract Research with OTAVA Research and Development Company

Institute of Molecular Biology and Genetics, the NAS of Ukraine has concluded Agreement concerning commercialization of scientific results with OTAVA Research and Development Company Ltd...

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Appeal to Publishers concerning affiliation “Crimea, Russia”

Scientific Researchers of the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, the NAS of Ukraine, support the appeal to publishers which publish...

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Contract Research with Novartis

The Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine has played a leading role in signing of Master Services Agreement with...

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Our research:

FGFR1 Inhibitors
N-phenylthieno[2,3-d]pyrimidin-4-amines Image
Thienopyrimidine derivatives have attracted great interest as protein kinase...



 

CK2 Inhibitors
4-aminothieno[2,3-d]pyrimidines Image
Novel CK2 inhibitors among 4-aminothieno[2,3-d]pyrimidines have been...



 

ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1 Image
Virtual screening and biochemical screening allowed us to identify...



 

Fluorescent Probes
Design of fluorescent dyes for biomedical applications Image
Search and development of novel highly efficient fluorescent probes for biology...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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