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Participation in the XI Ukrainian Biochemical Congress

PhD student at the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, Sergiy Starosyla, has attended the XI Ukrainian Biochemical Congress (October...

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Participation in the FEBS EMBO 2014 Conference

Scientific researcher at the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, Galyna Volynets, has attended the FEBS EMBO 2014 Conference (August 30 -...

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ASK1 Pharmacophore Model Derived from Diverse Classes of Inhibitors

Our manuscript on ASK1 pharmacophore model derived from diverse classes of inhibitors has been published in Bioorganic and Medicinal Chemistry Letters

Abstract: The three-dimensional...

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Design, synthesis and biological evaluation of naphthostyril derivatives as novel protein kinase FGFR1 inhibitors

Our manuscript on new FGFR1 inhibitors has been published in Journal of Enzyme Inhibition and Medicinal Chemistry

Abstract: New class of FGFR1 kinase inhibitors with naphthostyril...

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Our research:

ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1 Image
Virtual screening and biochemical screening allowed us to identify...



 

CK2 Inhibitors
2-phenylisothiazolidin-3-one-1,1-dioxides Image
We have synthesized 40 new 2-phenylisothiazolidin-3-one-1,1-dioxide...



 

FGFR1 Inhibitors
Oxindoles Image
Oxindoles are known class of inhibitors of RTK, including FGFR1. We perform...



 

Fluorescent Probes
Fluorescent detection of partially denatured conformation of beta-lactoglobuline Image
The native state of many proteins is known to be only marginally stable,...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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