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ABOUT Staff

Staff

The Department of Medicinal Chemistry now has 28 employees working full time. Among them, there are 12 scientists having PhD degree and 2 PhD Students.

yarmoluk2

Prof. Sergiy Yarmoluk

Head of Department of Medicinal Chemistry

 

Sergiy graduated from Chemical Department of Taras Shevchenko National University of Kyiv with Specialist degree in chemistry in 1979.

From 1979 until now Sergiy works in Institute of Molecular Biology and Genetics of National Academy of Sciences of Ukraine: in Protein Chemistry Department (since 1979), Oligonucleotides Synthesis Group (since 1983), Laboratory of Synthesis and Study of Biospecific Compounds (since 1985), Chemistry of Nucleic Acids Department (since 1993). In 1996 Sergiy became a Head of the Nucleic Acids Chemistry Research Group.

In 1993 Sergiy obtained Ph.D. degree in Bioorganic Chemistry. His Ph.D thesis was devoted to the synthesis and study of oligonucleotides modified with peptide residues.

In 2005 Sergiy Yarmoluk received Doctor's degree in Bioorganic Chemistry. The doctoral thesis title was: "Design of the Fluorescent Probes Based on Cyanine Dyes for Nucleic Acids and Proteins Detection". In 2006 Sergiy was given the rank of Professor in bioorganic chemistry.

Now Sergiy possesses position of the Head of Department of Medicinal Chemistry at the Institute of Molecular Biology and Genetics of National Academy of Sciences of Ukraine. He is a leader of a number of local and international research projects.

Research interests: design of protein kinase inhibitors with the aid of combinatorial chemistry, computer modeling and high-throughput screening; design of fluorescent probes for detection of biological macromolecules.

 

Dr. Volodymyr Bdzhola

Dr. Volodymyr Bdzhola

Deputy Head of Department of Medicinal Chemistry

 

In 1994 Volodymyr received Specialist degree in Chemistry, Chemical Department of Taras Shevchenko National University of Kyiv.

1998 – Ph.D degree in chemistry, Chemical Department of Kyiv Taras Shevchenko National University. His Ph.D. thesis was focused on the study of interaction of low coordinated phosphorus with metal alkoxides and alkoxyhalogenides.

Volodymyr have been working at the Institute of Molecular Biology and Genetics of National Academy of Sciences of Ukraine since 2001. Now he is a Senior Research Scientist,  Deputy Head of Department of Medicinal Chemistry. Volodymyr is a co-author of 65 publications in scientific journals.

 

Dr. Vladyslava Kovalska

Dr. Vladyslava Kovalska

Leader of Fluorescent Probes Design Group

 

In 1995 Vladyslava Kovalska obtained Specialist degree in chemistry, Natural Compounds Chemistry Division of Chemical Faculty at Taras Shevchenko National University of Kyiv. Since 1996 she works in the Institute of Molecular Biology and Genetics (Kyiv, Ukraine).

In 2000 Vladyslava obtained Ph.D degree in molecular biology. Her work was devoted to the interaction peculiarities of monomethine cyanine dyes with DNA, the studies were performed under supervising of acad. Prof. G. Matsuka and Dr. S. Yarmoluk

In 2012 Vladyslava defended the thesis of Doctor of Science in bioorganic chemistry "Fluorescent dyes for the detection of proteins of different folding degree" (advisor Prof. S. Yarmoluk).

Now Vladyslava Kovalska is a Senior Researcher of the Department of Medicinal Chemistry and is a Leader of Fluorescent Probes Design Group. Vladyslava is a co-author of about 70 papers published in scientific journals.

  

Dr. Sergiy Lukashov

Dr. Sergiy Lukashov

Leader of Chemical Synthesis Group

 

In 1997 Sergiy received Specialist degree in Chemistry (Chemical Department of Taras Shevchenko National University of Kyiv, specialization in Chemistry of Natural Compounds).

In 2003 Sergiy received Ph.D. degree in Bioorganic Chemistry under supervising of acad. Prof. G. Matsuka and Dr. S. Yarmoluk. His work was devoted to the synthesis of fluorescent cyanine dyes for detection of DNA.

Since 1997 until now Sergiy have been working in Institute of Molecular Biology and Genetics of National Academy of Sciences of Ukraine. Now he possesses position of the Senior Research Scientist of Department of Medicinal Chemistry. Sergiy is a co-author of more than 40 scientific papers. His current research interests focus on design and synthesis of small organic compounds targeting proteins kinases.

 

Our research:

ASK1 Inhibitors
Evaluation of 2-Thioxo-thiazolidin-4-ones Derivatives as Inhibitors of ASK1 Image
In order to discover novel ASK1 inhibitors we have performed screening program,...



 

CK2 Inhibitors
4,5,6,7-tetrahalogeno-1H-isoindole-1,3(2H)-diones (TID) Image
The novel potent and specific CK2 inhibitors -...



 

FGFR1 Inhibitors
Quinazolines Image
Quinazolines is another known class of RTK inhibitors that is widely...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

Fluorescent Probes
Design of fluorescent dyes for biomedical applications Image
Search and development of novel highly efficient fluorescent probes for biology...



 

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