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Protein Kinase Inhibitor Development
Molecular Design
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RESEARCH
CK2 Inhibitors
Aurone derivatives
1,3-thiazole-5-carboxylic acid derivatives
4-aminothieno[2,3-d]pyrimidines
2-aminopyrimidinones and their 6-aza-analogs
2-phenylisothiazolidin-3-one-1,1-dioxides
4'-hydroxyflavones
4,5,6,7-tetrahalogeno-1H-isoindole-1,3(2H)-diones (TID)
3-carboxy-4(1H)-quinolones
3-hydroxy-4'-carboxyflavone derivatives (FLC)
(thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids (TTP)
ASK1 Inhibitors
Identification of ASK1 inhibitors among the derivatives of Benzothiazol-2-yl-3-hydroxy-5-phenyl-1,5-dihydro-pyrrol-2-one
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1
Evaluation of 2-Thioxo-thiazolidin-4-ones Derivatives as Inhibitors of ASK1
FGFR1 Inhibitors
N-phenylnaphthostyril-1-sulfonamides
N-phenylthieno[2,3-d]pyrimidin-4-amines
Quinazolines
Oxindoles
Phenylbenzisoxazoles and aminopyrimidines
Flavones
Molecular Design
Molecular Design
Fluorescent Probes
Fluorescent dyes for study of beta-pleated protein formations
Fluorescent detection of partially denatured conformation of beta-lactoglobuline
Long-wavelength dyes for fluorescent detection of proteins
Design of fluorescent dyes for biomedical applications
Dyes for fluorescent detection of non-canonical DNA structures (triplexes and quadruplexes)
Compound Collection
Compound Collection
Our research:
FGFR1 Inhibitors
Flavones
One of the first discovered in the screening of inhibitors of FGFR1 classes are...
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ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1
Virtual screening and biochemical screening allowed us to identify...
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CK2 Inhibitors
3-hydroxy-4'-carboxyflavone derivatives (FLC)
With the aim to identify new CK2 inhibitors virtual screening of 150,000 small...
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Fluorescent Probes
Fluorescent dyes for study of beta-pleated protein formations
Uncontrolled proteins aggregation is considered to be the molecular basis for a...
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Molecular Design
Molecular Design
Molecular Design Laboratory of Medicinal Chemistry Department carry out...
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HOME
ABOUT
Overview
Staff
News and Events
RESEARCH
Protein Kinase Inhibitor Development
Molecular Design
Fluorescent Probes
Phytotherapy of Diseases Integrated Platform
PROJECTS
PUBLICATIONS
CONTACTS
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