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Participation in the 2nd Conference for Young Scientists (CYS-2017)

Young scientists from the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, Svitlana Chernii and Maryna Kuperman, participated in...

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Development of the Algorithm for Pharmacophore Model Optimization and Rescoring of Pharmacophore Screening Results

Scientific researchers of the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, the NAS of Ukraine, have developed the algorithm for pharmacophore...

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Participation in the XXXI Scientific Conference on Bioorganic Chemistry and Petrochemistry

Scientific researchers of the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, the NAS of Ukraine, Synyugin A.R., Prykhod'ko A.O., Sapelkin V.M....

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Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1

Our manuscript dedicated to the development of novel inhibitors of protein kinase FGFR1 has been published in Bioorganic and Medicinal Chemistry. 

Abstract: 

Fibroblast growth...

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Our research:

CK2 Inhibitors
2-aminopyrimidinones and their 6-aza-analogs Image
In order to find the new potent CK2 inhibitors 60 derivatives of...



 

FGFR1 Inhibitors
Oxindoles Image
Oxindoles are known class of inhibitors of RTK, including FGFR1. We perform...



 

ASK1 Inhibitors

 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

Fluorescent Probes
Fluorescent dyes for study of beta-pleated protein formations Image
Uncontrolled proteins aggregation is considered to be the molecular basis for a...



 

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