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Examining c-di-GMP and possible quorum sensing regulation in Pseudomonas fluorescens SBW25: links between intra- and inter-cellular regulation benefits community cooperative activities such as biofilm formation

Recently, the article dedicated to the investigation of possible role of bis-(3'-5')-cyclic dimeric  guanosine monophosphate (c-di-GMP) in quorum sensing regulation during biofilm...

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Participation in the XXIII Galyna Puchkovska International School-Seminar "Spectroscopy of Molecules and Crystals"

Young scientists from the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, Svitlana Chernii and Maryna Kuperman, participated in...

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Participation in the 2nd Conference for Young Scientists (CYS-2017)

Young scientists from the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, Svitlana Chernii and Maryna Kuperman, participated in...

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Development of the Algorithm for Pharmacophore Model Optimization and Rescoring of Pharmacophore Screening Results

Scientific researchers of the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, the NAS of Ukraine, have developed the algorithm for pharmacophore...

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Our research:

FGFR1 Inhibitors
Oxindoles Image
Oxindoles are known class of inhibitors of RTK, including FGFR1. We perform...



 

CK2 Inhibitors
Aurone derivatives Image
Novel CK2 inhibitors among benzylidenebenzofuran-3(2H)-one (aurone) derivatives...



 

ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1 Image
Virtual screening and biochemical screening allowed us to identify...



 

Fluorescent Probes
Fluorescent detection of partially denatured conformation of beta-lactoglobuline Image
The native state of many proteins is known to be only marginally stable,...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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