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ASK1 Pharmacophore Model Derived from Diverse Classes of Inhibitors

Our manuscript on ASK1 pharmacophore model derived from diverse classes of inhibitors has been published in Bioorganic and Medicinal Chemistry Letters

Abstract: The three-dimensional...

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Design, synthesis and biological evaluation of naphthostyril derivatives as novel protein kinase FGFR1 inhibitors

Our manuscript on new FGFR1 inhibitors has been published in Journal of Enzyme Inhibition and Medicinal Chemistry

Abstract: New class of FGFR1 kinase inhibitors with naphthostyril...

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Participation in the VIII Conference for young scientists of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, dedicated to the 90th anniversary of the birth of Kostyuk Platon Grygorovych

Scientific researchers at the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, Andriy Gryshchenko and Olga Ostrynska, participated in the work of VIII...

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Participation in the ХХIX Scientific Сonference on Bioorganic Chemistry and Petrochemistry

PhD Student at the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, Anatoliy Synyugin, participated in the work of ХХIX Scientific Conference on...

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Our research:

ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1 Image
Virtual screening and biochemical screening allowed us to identify...



 

FGFR1 Inhibitors
Oxindoles Image
Oxindoles are known class of inhibitors of RTK, including FGFR1. We perform...



 

CK2 Inhibitors
Aurone derivatives Image
Novel CK2 inhibitors among benzylidenebenzofuran-3(2H)-one (aurone) derivatives...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

Fluorescent Probes
Fluorescent dyes for study of beta-pleated protein formations Image
Uncontrolled proteins aggregation is considered to be the molecular basis for a...



 

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