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Participation in the XXXI Scientific Conference on Bioorganic Chemistry and Petrochemistry

Scientific researchers of the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, the NAS of Ukraine, Synyugin A.R., Prykhod'ko A.O., Sapelkin V.M....

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Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1

Our manuscript dedicated to the development of novel inhibitors of protein kinase FGFR1 has been published in Bioorganic and Medicinal Chemistry. 

Abstract: 

Fibroblast growth...

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Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1

Our paper dedicated to the development of novel inhibitors of protein kinase FGFR1 has been published in Bioorganic and Medicinal Chemistry. 

Abstract: 

Fibroblast growth...

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Contract Research with OTAVA Research and Development Company

Institute of Molecular Biology and Genetics, the NAS of Ukraine has concluded Agreement concerning commercialization of scientific results with OTAVA Research and Development Company Ltd...

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Our research:

FGFR1 Inhibitors
Flavones Image
One of the first discovered in the screening of inhibitors of FGFR1 classes are...



 

ASK1 Inhibitors
Evaluation of 2-Thioxo-thiazolidin-4-ones Derivatives as Inhibitors of ASK1 Image
In order to discover novel ASK1 inhibitors we have performed screening program,...



 

CK2 Inhibitors
3-carboxy-4(1H)-quinolones Image
This CK2 inhibitors were revealed and evaluated to be a CK2 inhibitors after...



 

Fluorescent Probes
Fluorescent dyes for study of beta-pleated protein formations Image
Uncontrolled proteins aggregation is considered to be the molecular basis for a...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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