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Participation in the XXXI Scientific Conference on Bioorganic Chemistry and Petrochemistry

Scientific researchers of the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics, the NAS of Ukraine, Synyugin A.R., Prykhod'ko A.O., Sapelkin V.M....

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Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1

Our manuscript dedicated to the development of novel inhibitors of protein kinase FGFR1 has been published in Bioorganic and Medicinal Chemistry. 

Abstract: 

Fibroblast growth...

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Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1

Our paper dedicated to the development of novel inhibitors of protein kinase FGFR1 has been published in Bioorganic and Medicinal Chemistry. 

Abstract: 

Fibroblast growth...

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Contract Research with OTAVA Research and Development Company

Institute of Molecular Biology and Genetics, the NAS of Ukraine has concluded Agreement concerning commercialization of scientific results with OTAVA Research and Development Company Ltd...

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Our research:

FGFR1 Inhibitors
Quinazolines Image
Quinazolines is another known class of RTK inhibitors that is widely...



 

ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1 Image
Virtual screening and biochemical screening allowed us to identify...



 

CK2 Inhibitors
Aurone derivatives Image
Novel CK2 inhibitors among benzylidenebenzofuran-3(2H)-one (aurone) derivatives...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

Fluorescent Probes
Design of fluorescent dyes for biomedical applications Image
Search and development of novel highly efficient fluorescent probes for biology...



 

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