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Participation in the bioGENext Conference

Senior research scientist from the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, Galyna Volynets, participated in the...

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Participation in the Les Houches - TSRC - FEBS Workshop on Protein Dynamics

Senior research scientist from the Department of Medicinal Chemistry of the Institute of Molecular Biology and Genetics of the NAS of Ukraine, Galyna Volynets, participated in the Les...

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Identification of novel antistaphylococcal hit compounds

Recently, the article dedicated to the development of novel antistaphylococcal agents targeting seryl-tRNA synthetase has been published.

Abstract:

Staphylococcus aureus is...

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Identification of dual-targeted Mycobacterium tuberculosis aminoacyl-tRNA synthetase inhibitors using machine learning

Recently, the article dedicated to the development of novel antituberculosis agents targeting aminoacyl-tRNA synthetases using machine learning approach has been...

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Our research:

ASK1 Inhibitors
Evaluation of 2-Thioxo-thiazolidin-4-ones Derivatives as Inhibitors of ASK1 Image
In order to discover novel ASK1 inhibitors we have performed screening program,...



 

CK2 Inhibitors
2-aminopyrimidinones and their 6-aza-analogs Image
In order to find the new potent CK2 inhibitors 60 derivatives of...



 

FGFR1 Inhibitors
Oxindoles Image
Oxindoles are known class of inhibitors of RTK, including FGFR1. We perform...



 

Fluorescent Probes
Fluorescent dyes for study of beta-pleated protein formations Image
Uncontrolled proteins aggregation is considered to be the molecular basis for a...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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