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RESEARCH Protein Kinase Inhibitors

Protein Kinase Inhibitors

"Kinome" is a depository of promising drug targets - protein kinases, which control vast diversity of molecular interactions in cell life. Indeed, numerous reports describing the discovery of new pharmaceutical substances targeting protein kinases have been published during last few years. Some of these substances are being tested in clinical trials, some of them are already on the market.

Our Department has been involved in extensive research and development of inhibitors for various protein kinases:

Other kinase inhibitors research:

CK2 Inhibitors
3-carboxy-4(1H)-quinolones Image
This CK2 inhibitors were revealed and evaluated to be a CK2 inhibitors after...



 

FGFR1 Inhibitors
Quinazolines Image
Quinazolines is another known class of RTK inhibitors that is widely...



 

ASK1 Inhibitors
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as Inhibitors of ASK1 Image
Virtual screening and biochemical screening allowed us to identify...



 

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