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ABOUT News and Events Grant Project “Target-oriented search of aminoacyl-tRNA synthetase inhibitors with selective action toward causative agents of human infectious diseases” has been started

Grant Project “Target-oriented search of aminoacyl-tRNA synthetase inhibitors with selective action toward causative agents of human infectious diseases” has been started

We have started working on project "Target-oriented search of aminoacyl-tRNA synthetase inhibitors with selective action toward causative agents of human infectious diseases" in cooperation with the Department of Protein Synthesis Enzymology of the Institute of Molecular Biology and Genetics of the NAS of Ukraine in frame of grant of interdisciplinary program of scientific investigations of the NAS of Ukraine (2015-2019).

Our research:

ASK1 Inhibitors
Evaluation of 2-Thioxo-thiazolidin-4-ones Derivatives as Inhibitors of ASK1 Image
In order to discover novel ASK1 inhibitors we have performed screening program,...



 

CK2 Inhibitors
(thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids (TTP) Image
To study CK2 inhibitory activity of substituted (thieno[2,3-d]...



 

FGFR1 Inhibitors
N-phenylthieno[2,3-d]pyrimidin-4-amines Image
Thienopyrimidine derivatives have attracted great interest as protein kinase...



 

Fluorescent Probes
Fluorescent detection of partially denatured conformation of beta-lactoglobuline Image
The native state of many proteins is known to be only marginally stable,...



 

Molecular Design
Molecular Design Image
Molecular Design Laboratory of Medicinal Chemistry Department carry out...



 

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