logo
English (United Kingdom)Ukrainian (UA)
ПУБЛІКАЦІЇ

Публікації

ПАТЕНТИ:

  1. Pat. 117279, 26.06.2017. Novel small-molecular organic compounds with antituberculosis activity based on isonicotinic acid hydrazide. Volynets GP, Tukalo MA, Bdzhola VG, Tarnavskiy SS, Starosyla SA, Gudzera OY, Yarmoluk SM.
  2. Pat. 116134, 10.05.2017. Novel small-molecular organic compounds with antituberculosis activity based on benzaldehyde thiosemicarbazone. Volynets GP, Tukalo MA, Bdzhola VG, Starosyla SA, Tarnavskiy SS, Gudzera OY, Kriklivyi IA, Yarmoluk SM. 
  3. Pat. 86041, 10.12.2013. Low-molecular organic ATP-competitive inhibitors of serine/threonine kinase CK2 based on 4-aminothieno-[2,3-d]pyrimidine heterocycle. Ostrynska OV, Balanda AO, Bdzhola VG, Kotey IM, Kukharenko OP, Yarmoluk SM.
  4. Pat. WO2011/065980 (A2), 03.06.2011. Dyes for Analysis of Protein Aggregation.  Patton WF; Yarmoluk SM; Pande P; Kovalska V; Dai L; Volkova K; Coleman L; Losytskyy M; Ludlam A; Balanda A; Shen D.
  5. Patent Application US2008091015 A1, 17.04.2008; WO 2008/027821 A1, 06.03.2008. Use of squaraine dyes to visualize protein during separations. Berkelman TR, Yarmoluk SM, Kovalska VB, Losytskyy MYu, Volkova KD.
  6. Patent Application US2006207881, 21.09.2006. Detection of polyamino acids using trimethincyanine dyes. Kovalska VB; Kryvorotenko DV; Losytskyy MYu; Nording P; Rueck A; Schoenenberger B; Yarmoluk SM; Wahl F. 
  7. Pat. 2004031889. 15.02.2005. Bull. №2. Compound 5-[(4-chlorophenyl)methylidene]-2-(4-oxyanilino)-4,5-dihydrothiazol-4-one, which possess anticancer activity. Lesyk RB, Zimenkovsky BS, Yarmoluk SM, Bdzhola VH, Vovk ОІ.  
  8. Pat. UА68984 А, C07D215/00, 2004-08-16. Application of 4-substituted 3-carboxyquinolines as protein kinase CK2 inhibitors. Sapelkin VM, Lukashov SS, Golub AG, Bdzhola VG, Yakovenko OYa, Yarmoluk SM, Dubinina GG.
  9. Pat. UA69165 А, С07D215/00, 2004-08-16. Application of 4,5,6,7-tetrahalogeno-1,3-isoindolinediones as protein kinase CK2 inhibitors. Golub AG, Yakovenko OYa, Yarmoluk SM, Dubinina GG, Bdzhola VG, Prykhod'ko AO.
  10. Patent Application US2003175988, 18. 09.2003. Method and compounds for the fluorescent labelling of biomolecules and polymer particles. Yarmoluk SM, Kostenko OM, Tolmachev OI, Wolfbeis OS. 
  11. Pat. 61626A (UA). Cl. C07D207/444, A61K31/40 19.03.2003. The structures with antitumor activity among 1-benzyl-3-chloro-4-anilino-2,5-dihydro-1H-2,5-pyrroledione derivatives. Tarnavsky SS, Golovach SM, Dubinina GG, Yarmoluk SM.

ВИБРАНІ ПУБЛІКАЦІЇ:

  1. Protopopov MV, Volynets GP, Starosyla SA, Vdovin VS, Lukashov SS, Bilokin YV, Bdzhola VG, Yarmoluk SM (2018) Identification of 1,3-thiazole-5-carboxylic acid derivatives as inhibitors of protein kinase CK2. Curr Enzyme Inhib 14(2):152-159.
  2. Moshynets OV, Foster D, Karakhim SA, McLaughlin K, Rogalsky SP, Rymar SY, Volynets GP, Spiers AJ (2018) Examining c-di-GMP and possible quorum sensing regulation in Pseudomonas fluorescens SBW25: links between intra- and inter-cellular regulation benefits community cooperative activities such as biofilm formation. Ukr Biochem J 90(3):17-31. 
  3. Losytskyy M, Akbay N, Chernii S, Avci E, Chernii V, Yarmoluk S, Culha M, Kovalska V (2018) Characterization of the interaction between phthalocyanine and amyloid fibrils by surface-enhanced raman scattering (SERS). Anal Lett 51(1-2):221-228.
  4. Kovalska VB, Vakarov SV, Kuperman MV, Losytskyy MY, Gumienna-Kontecka E, Voloshin YZ, Varzatskii OA (2018) Induced chirality of cage metal complexes switched by their supramolecular and covalent binding. Dalton Transactions 47(4) doi: 10.1039/C7DT03731G.
  5. Kovalska V, Chernii S, Losytskyy M, Tretyakova I, Dovbii Y, Gorski A, Chernii V, Czerwieniec R, Yarmoluk S (2018) Design of functionalized β-ketoenole derivatives as efficient fluorescent dyes for detection of amyloid fibrils. New J Chem doi: 10.1039/C8NJ01020J.
  6. Protopopov MV, Ostrynska OV, Starosyla SA, Vodolazhenko MA, Sirko SM, Gorobets NY, Bdzola VG, Desenko SM, Yarmoluk SM (2018) Dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-4-ones as a new class of CK2 inhibitors. Mol Div doi: 10.1007/s11030-018-9836-1.
  7. Kovalska  V, Chernii S, Losytskyy M, Ostapko J, Tretyakova I, Gorski A, Chernii V, Yarmoluk S (2018) Activity of Zn and Mg phthalocyanines and porphyrazines in amyloid aggregation of insulin. J Mol Recog 31(1) doi: 10.1002/jmr.2660.
  8. Yoon JH, Mo JS, Kim MY, Ann EJ, Ahn JS, Jo EH, Lee HJ, Lee YC, Seol W, Yarmoluk SM, Gasser T, Kahle PJ, Liu GH, Belmonte JCI, Park HS (2017) LRRK2 functions as a scaffolding kinase of ASK1-mediated neuronal cell death. Biochim Biophys Acta Mol Cell Res 1864(12):2356-2368. 
  9. Protopopov MV, Ostrynska OV, Ivanchenko DH, Starosyla SA, Bdzhola VG, Romanenko MI, Yarmoluk SM (2017) Search of protein kinase CK2 inhibitors based on purine-2,6-diones derivatives. Ukr Biochem J 89(5):32-39.
  10. Kuperman M, Chernii S, Varzatskii O, Zhdanov A, Bykov A, Zhizhin K, Yarmoluk S, Kovalska V (2017) The discovery of the effect of closo-borate on amyloid fibril formation. ChemistrySelect 2(34):10965-10970.
  11. Kuperman MV, Losytskyy MYu, Bykov AYu, Yarmoluk SM, Zhizhin KYu, Kuznetsov NT, Varzatskii OA, Gumienna-Kontecka E, Kovalska VB (2017) Effective binding of perhalogenated closo-borates to serum albumins revealed by spectroscopic and ITC studies. J Mol Struct 1141:75-80.
  12. Kovalska V, Chernii S, Cherepanov V, Losytskyy M, Chernii V, Varzatskii O, Naumovets A, Yarmoluk S (2017) The impact of binding of macrocyclic metal complexes on amyloid fibrillization of insulin and lysozyme. J Mol Recog 30(8) doi: 10.1002/jmr.2622.
  13. Tatikolov AS, Akimkin TM, Panova IG, Yarmoluk SM (2017) Spectral-fluorescent study of the interaction of the polymethine dye probe Cyan 2 with chondroitin-4-sulfate. Spectrochim Acta A Mol Biomol Spectroscopy 177:93-96.
  14. Niefind K, Bischoff N, Golub AG, Bdzhola VG, Balanda AO, Prykhod'ko AO, Yarmoluk SM (2017) Structural hypervariability of the two human protein kinase CK2 catalytic subunit paralogs revealed by complex structures with a flavonol- and a thieno[2,3-d]pyrimidine-based inhibitor. Pharmaceuticals (Basel) 10(1):pii:E9. 
  15. Zinchenko AN, Muzychka LV, Smolii OB, Bdzhola VG, Protopopov MV, Yarmoluk SM (2017) Synthesis and biological evaluation of novel amino-substituted derivatives of pyrido[2,3-d]pyrimidine as inhibitors of protein kinase CK2. Biopolym Cell 33(5):367-378.
  16. Protopopov MV, Starosyla SA, Borovykov OV, Sapelkin VN, Bilokin YV, Bdzhola VG, Yarmoluk SM (2017) Hit identification of CK2 inhibitors by methods of virtual screening. Biopolym Cell 33(4):291-301. 
  17. Kuperman M, Chernii S, Varzatskii O, Zhdanov A, Bykov A, Zhizhin K, Yarmoluk S, Kovalska V (2017) The discovery of the effect of closo-borate on amyloid fibril formation. ChemistrySelect 2(34):10965-10970.
  18. Syniugin AR, Ostrynska OV, Chekanov MO, Volynets GP, Starosyla SA, Bdzhola VG, Yarmoluk SM (2016) Design, synthesis and evaluation of 3-quinoline carboxylic acids as new inhibitors of protein kinase CK2. J Enzyme Inhib Med Chem 31:160-169.
  19. Volynets GP, Gorbatiuk OB, Kukharenko OP, Usenko MO, Yarmoluk SM (2016) Production of recombinant human apoptosis signal-regulating kinase 1 (ASK1) in Escherichia coli. Prot Expr Purif 126:89-92.
  20. Syniugin AR, Chekanov MO, Savitskiy PV, Pashenko AE, Zhuk TS, Yarmoluk SM, Fokin AA (2016) New method for the synthesis of pyrrolo[2,3-b]dihydroquinolines. Tetrahedron Lett 57(2):213-215.
  21. Kovalska V, Chernii S, Losytskyy M, Dovbii Y, Tretyakova I, Czerwieniec R, Chernii V, Yarmoluk S, Volkov S (2016) b-ketoenole dyes: synthesis and study as fluorescent sensors for protein amyloid aggregates. Dyes and Pigments 132:274-281.
  22. Gudzera OI, Golub AG, Bdzhola VG, Volynets GP, Kovalenko OP, Boyarshin KS, Yaremchuk AD, Protopopov MV, Yarmoluk SM, Tukalo MA (2016) Identification of Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS) inhibitors among the derivatives of 5-phenylamino-2H-[1,2,4]triazin-3-one. J Enzyme Inhib Med Chem doi: 10.1080/14756366.2016.1190712.
  23. Gryshchenko AA, Tarnavskiy SS, Levchenko KV, Bdzhola VG, Volynets GP, Golub AG, Ruban TP, Vygranenko KV, Lukash LL, Yarmoluk SM (2016) Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1. Bioorg Med Chem 24(9):2053-2059.
  24. Gudzera OI, Golub AG, Bdzhola VG, Volynets GP, Lukashov SS, Kovalenko OP, Kriklivyi IA, Yaremchuk AD, Starosyla SA, Yarmoluk SM, Tukalo MA (2016) Discovery of potent anti-tuberculosis agents targeting leucyl-tRNA synthetase. Bioorg Med Chem 24(5):1023-1031.
  25. Ostrynska OV, Balanda AO, Bdzhola VG, Golub AG, Kotey IM, Kukharenko OP, Gryshchenko AA, Briukhovetska NV, Yarmoluk SM (2016) Design and synthesis of novel protein kinase CK2 inhibitors on the base of 4-aminothieno[2,3-d]pyrimidines. Eur J Med Chem 115:148-160.
  26. Losytskyy MYu, Kovalska VB, Varzatskii OA, Kuperman MV, Potocki S, Gumienna-Kontecka E, Zhdanov AP, Yarmoluk SM, Voloshin YZ, Zhizhin KYu, Kuznetsov NT, Elskaya AV (2016) An interaction of the functionalized closo-borates with albumins: The protein fluorescence quenching and calorimetry study. J Luminesc 169:51-60.  
  27. Starosyla SA, Volynets GP, Lukashov SS, Gorbatiuk OB, Golub AG, Bdzhola VG, Yarmoluk SM (2015) Identification of apoptosis signal-regulating kinase 1 (ASK1) inhibitors among the derivatives of benzothiazol-2-yl-3-hydroxy-5-phenyl-1,5-dihydro-pyrrol-2-one. Bioorg Med Chem 23(10):2489-2497. 
  28. Guerra B, Bischoff N, Bdzhola VG, Yarmoluk SM, Issinger OG, Golub AG, Niefind K (2015) A note of caution on the role of halogen bonds for protein kinase/inhibitor recognition suggested by high- and low-salt CK2α complex structures. ACS Chem Biol 10(7):1654-1660.
  29. Kuperman MV, Chernii SV, Losytskyy MYu, Kryvorotenko DV, Derevyanko NO, Slominskii YuL, Kovalska VB, Yarmoluk SM (2015) Trimethine cyanine dyes as fluorescent probes for amyloid fibrils: The effect of N,N'-substituents. Analytical Biochemistry 484:9-17.
  30. Gryshchenko AA, Bdzhola VG, Balanda AO, Briukhovetska NV, Kotey IM, Golub AG, Ruban TP, Lukash LL, Yarmoluk SM (2015) Design, synthesis and biological evaluation of N-phenylthieno[2,3-d]pyrimidin-4-amines as inhibitors of FGFR1. Bioorg Med Chem 23(9):2287-2293.
  31. Gryshchenko AA, Levchenko KV, Bdzhola VG, Ruban TP, Lukash LL, Yarmoluk SM (2015) Design, synthesis and biological evaluation of naphthostyril derivatives as novel protein kinase FGFR1 inhibitors. J Enzyme Inhib Med Chem 30(1):126-132.
  32. Starosyla SA, Volynets GP, Bdzhola VG, Golub AG, Yarmoluk SM (2014) Pharmacophore approaches in protein kinase inhibitors design. World J Pharmacol 3(4):162-173. 
  33. Starosyla SA, Volynets GP, Bdzhola VG, Golub AG, Protopopov MV, Yarmoluk SM (2014) ASK1 pharmacophore model derived from diverse classes of inhibitors. Bioorg Med Chem Lett 24(18):4418-4423.
  34. Vukomanovic D, Rahman MN, Bilokin Y, Golub AG, Brien JF, Szarek WA, Jia Z, Nakatsu K (2014) In vitro Activation of heme oxygenase-2 by menadione and its analogs. Med Gas Res 4(1):4.
  35. Chekanov MO, Ostrynska OV, Synyugin AR, Bdzhola VG, Yarmoluk SM (2014) Design, synthesis and evaluation of 2-phenylisothiazolidin-3-one-1,1-dioxides as a new class of human protein kinase CK2 inhibitors. J Enzyme Inhib Med Chem 29(3):338-343.
  36. Kovalska VB, Losytskyy MY, Varzatskii OA, Cherepanov VV, Voloshin YZ, Mokhir AA, Yarmoluk SM, Volkov SV (2014) Study of anti-fibrillogenic activity of iron(II) clathrochelates. Bioorg Med Chem 22(6):1883-1888.
  37. Inshyn DI, Kovalska VB, Losytskyy MY, Slominskii YL, Tolmachev OI, Yarmoluk SM (2014) Development of a quantitative structure activity relations (QSAR) model to guide the design of fluorescent dyes for detecting amyloid fibrils. Biotech and Histochem 89(1):1-7.
  38. Kovalska VB, Losytskyy MYu, Reis LV, Santos PF, Yarmoluk SM (2014) Fluorescent detection of a partially unfolded conformation of beta-lactoglobulin using squaraine dyes. Macromol Symp 335(1):43-50. 
  39. Kovalska V, Cherepanov V, Losytskyy M, Chernii S, Senenko A, Chernii V, Tretyakova I, Yarmoluk S, Volkov S (2014) Anti-fibrillogenic properties of phthalocyanines: Effect of the out-of-plane ligands. Bioorg Med Chem 22(24):6918-6923. 
  40. Chekanov MO, Ostrynska OV, Tarnavskyi SS, Synyugin AR, Briukhovetska NV, Bdzhola VG, Pashenko AE, Fokin AA, Yarmoluk SM (2013) Design, synthesis and biological evaluation of 2-aminopyrimidinones and their 6-aza-analogs as a new class of CK2 inhibitors. J Enzyme Inhib Med Chem. 29(5):639-646.
  41. Volynets G, Bdzhola V, Golub A, Synyugin A, Chekanov M, Kukharenko O, Yarmoluk S (2013) Rational Design of Apoptosis Signal-Regulating Kinase 1 Inhibitors: Discovering Novel Structural Scaffold. Eur J Med Chem 61:104-115.
  42. Golub AG, Bdzhola VG, Ostrynska OV, Kyshenia IV, Sapelkin VM, Prykhod’ko AO, Kukharenko OP, Yarmoluk SM (2013) Discovery and characterization of synthetic 4’-hydroxyflavones – New CK2 inhibitors from flavone family. Bioorg Med Chem 21:6681-6689.
  43. Hunnigan K, Kulkarni SS, Bdzhola VG, Golub AG, Yarmoluk SM, Talele TT (2013) Identification of novel PARP-1 inhibitors by structure-based virtual screening. Bioorg Med Chem Lett 23:5790-5794.
  44. Kovalska VB, Losytskyy MY, Chernii SV, Chernii VY, Tretyakova IM, Yarmoluk SM, Volkov SV (2013) Towards the anti-fibrillogenic activity of phthalocyanines with out-of-plane ligands: Correlation with self-association proneness. Biopolym Cell 29(6):473-479.
  45. Losytskyy MY, Kovalska VB, Varzatskii OA, Sergeev AM, Yarmoluk SM, Voloshin YZ (2013) Interaction of the iron(II) cage complexes with proteins: Protein fluorescence quenching study. J Fluoresc 23(5):889-895.
  46. Golub AG, Gurukumar KR, Basu A, Bdzhola VG, Bilokin Y, Yarmoluk SM, Lee J-C, Talele TT, Nichols DB, Kaushik-Basu N (2012) Discovery of New Scaffolds for Rational Design of HCV NS5B Polymerase Inhibitors. Eur J Med Chem 58:258-264.
  47. Martić S, Tackenburg S, Bilokin Y, Golub A, Bdzhola V, Yarmoluk S, Kraatz HB (2012) Electrochemical screening of the indole/quinolone derivatives as potential protein kinase CK2 inhibitors. Anal Biochem 421(2):617-621.
  48. Gryshchenko AA, Bdzhola VG, Balanda AO, Lukashov SS, Fesun IM, Yarmoluk SM (2012) Inhibitors of protein kinase FGFR1 from phenylhydrazine class. Ukrainica Bioorganica Acta 1:48-50.
  49. Kovalska VB, Losytskyy MY, Tolmachev OI, Slominskii YL, Segers-Nolten GMJ, Subramaniam V, Yarmoluk SM (2012) Tri- and pentamethine cyanine dyes for fluorescent detection of α-synuclein oligomeric aggregates. J Fluoresc 22(6):1441-1448.
  50. Kovalska V, Losytskyy M, Chernii V, Volkova K, Tretyakova I, Cherepanov V, Yarmoluk S, Volkov S (2012) Bioorg Med Chem 20(1):330-334. 
  51. Golub AG, Bdzhola VG, Kyshenia YV, Sapelkin VM, Prykhod'ko AO, Kukharenko OP, Ostrynska OV, Yarmoluk SM (2011) Structure-based discovery of novel flavonol inhibitors of human protein kinase CK2. Mol Cell Biochem 356(1-2):107-115.
  52. Volynets GP, Chekanov MO, Synyugin AR, Golub AG, Kukharenko OP, Bdzhola VG, Yarmoluk SM (2011) Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as inhibitors of apoptosis signal-regulating kinase 1 (ASK1). Med Chem 54(8):2680-2686.
  53. Golub AG, Bdzhola VG, Briukhovetska NV, Balanda AO, Kukharenko OP, Kotey IM, Ostrynska OV, Yarmoluk SM (2011) Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2. Eur J Med Chem 46(3):870-876.
  54. Kramerov AA, Golub AG, Bdzhola VG, Yarmoluk SM, Ahmed K, Bretner M, Ljubimov AV (2011) Treatment of cultured human astrocytes and vascular endothelial cells with protein kinase CK2 inhibitors induces early changes in cell shape and cytoskeleton. Mol Cell Biochem 349(1-2):125-137.
  55. Volkova KD, Kovalska VB, Losytskyy MYu, Reis LV, Santos PF, Almeida P, Lynch DE, Yarmoluk SM (2011) Aza-substituted squaraines for the fluorescent detection of albumins. Dyes and Pigments 90:41-47.
  56. Kovalska VB, Losytskyy MYu, Yarmoluk SM, Lubitz I, Kotlyar AB (2011) Mono and trimethine cyanines cyan 40 and Cyan 2 as probes for highly selective fluorescent detection of non-canonical DNA structures. J Fluoresc 21(1):223-230.
  57. Volkova KD, Kovalska VB, Inshin D, Slominskii YL, Tolmachev OI, Yarmoluk SM (2011) Novel fluorescent trimethine cyanine dye 7519 for amyloid fibril inhibition assay. Biotech Histochem 86(3):188-191.
  58. Volynets GP, Bdzhola VG, Kukharenko OP, Yarmoluk SM (2010) Identification of ASK1 small-molecule inhibitors. Ukr Biochim J 82(5):41-50.
  59. Kovalska VB, Losytskyy MYu, Lubitz I, Kotlyar AB, Yarmoluk SM (2010) Mono and trimethine cyanines Cyan 40 and Cyan 2 as probes for highly selective fluorescent detection of non-canonical DNA structures. J Fluoresc 21(1):223-230.
  60. Kovalska VB, Volkova KD, Manaev AV, Losytskyy MYu, Okhrimenko IN, Traven VF, Yarmoluk SM (2010) 2-Quinoline and coumarin polymethines for the detection of proteins using fluorescence. Dyes and Pigments 84:159-164.
  61. Tokar VP, Losytskyy MYu, Ohulchanskyy TY, Kryvorotenko DV, Kovalska VB, Balanda AO, Dmytruk IM, Yashchuk VM, Yarmoluk SM (2010) Styryl dyes as two-photon excited fluorescent probes for DNA detection and two-photon laser scanning fluorescence microscopy of living cells. J Fluoresc 20(4):865-872.
  62. Volynets GP, Bdzhola VG, Yarmoluk SM (2010) Methods of structural bioinformatics. Biotechnology 3(4):9-19.
  63. Grischenko AA, Bdzhola VG, Kukharenko OP, Yarmoluk SM (2009) Search for FGFR1 inhibitors among chromone derivatives. Ukrainica Bioorganica Acta 7(2):64-68.
  64. Volynets GP, Bdzhola VG, Kukharenko OP, Sovetova OV, Yarmoluk SM (2009) Protein kinase ASK1 as potential therapeutic target. Biopolymers and Cell 25(3):169-180.
  65. Golub AG, Yakovenko OYa, Prykhod'ko AO, Lukashov SS, Bdzhola VG, Yarmoluk SM (2008) Evaluation of 4,5,6,7-tetrahalogeno-1H-isoindole-1,3(2H)-diones as inhibitors of human protein kinase CK2. Biochimica et Biophysica Acta 1784(1): 143–149.
  66. Kotey IM, Balanda AO, Bdzhola VG, Lukashov SS, Kukharenko OP, Kharchenko VM, Yarmoluk SM (2008) Synthesis and biologic evaluation of thienopyrimidinones inhibition activity against protein kinase CK2. Ukrainica Bioorganica Acta 6(2):3-9.
  67. Shablykin OV, Kucharenko OP, Iakovenko IN, Yarmoluk SM, Brovarets VS (2008) Search for specific protein kinase СК2 inhibitors and vasoactive compounds among 5-amino-1,3-oxazoles derivatives. Ukrainica Bioorganica Acta 6(1):28-36.
  68. Yakovenko O, Оliferenko A, Bdzhola V, Palyulin V, Zefirov N (2008) Kirchhoff atomic charges fitted to multipole moments: Implementation for a virtual screening system. Journal of Computational Chemistry 29:1332-1343.
  69. Volkova KD, Kovalska VB, Balanda AO, Slominskii YuL, Tolmachev OI, Subramaniam V, Yarmoluk SM (2008) Studies of mono- and trimethine cyanine dyes as specific fluorescent probes for fibrillarβ-lactoglobulin detection. Ukrainica Bioorganica Acta 6(2):15-21.
  70. Volkova KD, Kovalska VB, Segers-Nolten GM, Veldhuis G, Subramaniam V, Yarmoluk SM (2008) Explorations of the application of cyanine dyes for quantitative alpha-synuclein detection. Biotechnic & Histochemistry 84(2):55-61.
  71. Volkova KD, Kovalska VB, Losytskyy MYu, Bento A, Reis LV, Santos PF, Almeida P, Yarmoluk SM (2008) Studies of benzothiazole and benzoselenazole squaraines as fluorescent probes for albumins detection.Journal of Fluorescence 18(5):877-882.
  72. Yarmoluk SM, Kovalska VB, Losytskyy My (2008) Symmetric cyanine dyes for detecting nucleic acids.Biotechnic and Histochemistry 83(3-4):131-145.
  73. Volkova KD, Kovalska VB, Balanda AO, Losytskyy MYu, Golub AG, Vermeij RJ, Subramaniam V, Tolmachev OI, Yarmoluk SM (2008) Specific fluorescent detection of fibrillar α-synuclein using mono- and trimethine cyanine dyes. Bioorganic and Medicinal Chemistry 16(3):1452-1459.
  74. Akbay N, Losytskyy MYu, Kovalska VB, Balanda AO, Yarmoluk SM (2008) The mechanism of benzothiazole styrylcyanine dyes binding with dsDNA: studies by spectral-luminescent methods. Journal of Fluorescence 18(1):139-147.
  75. Volkova KD, Kovalska VB, Yarmoluk SM (2007) Modern techniques for protein detection on polyacrylamide gels: problems arising from the use of dyes of undisclosed structures for scientific purposes. Biotechnic and Histochemistry 82(4&5):201-208.
  76. Volkova KD, Kovalska VB, Balanda AO, Vermeij RJ, Subramaniam V, Slominskii YuL, Yarmoluk SM (2007) Cyanine dye-protein interactions: looking for fluorescent probes for amyloid structures. Journal of Biochemical and Biophysical Methods 70(5):727-733.
  77. Xu C, Losytskyy MYu, Kovalska VB, Kryvorotenko DV, Yarmoluk SM, McClelland S, Bianco PR (2007) Novel, monomeric cyanine dyes as reporters for DNA helicase activity. Journal of Fluorescence 17(6):671-685.
  78. Yashchuk VM, Gusak VV, Dmytruk IM, Prokopets VM, Kudrya VYu, Losytskyy MYu, Tokar VP, Gumenyuk YaO, Yarmoluk SM, Kovalska VB, Balanda AO, Kryvorotenko DV (2007) Two-photon excited luminescent styryl dyes as probes for the DNA detection and imaging. Photostability and phototoxic influence on DNA.Molecular Crystals and Liquid Crystals 467(1):325-338.
  79. Yashchuk VM, Kudrya VYu, Losytskyy MYu, Tokar VP, Yarmoluk SM, Dmytruk IM, Prokopets VM, Kovalska VB, Balanda AO, Kryvorotenko DV, Ogul'chansky TYu (2007) The optical biomedical sensors for DNA detection and imaging based on two-photon excited luminescent styryl dyes: phototoxic influence on the DNA.SPIE 6796.
  80. Prostota YaO, Kachkovsky YaO, Kropachev AV, Losytskyy MYu, Tarnavskyy SS, Yarmoluk SM (2007) Polymethine dyes – derivatives of the 7-N,N-dialkylaminocoumarines. Ukrainica Bioorganica Acta 5(1):32-42.
  81. Losytskyy MYu, Akbay N, Kovalska VB, Balanda AO, Boutorine A, Yarmoluk SM (2007) To the studies of (p-dimethylaminostyryl)pyridinium based homodimer to dsDNA binding mechanism. Ukrainica Bioorganica Acta 5(2):52-55.
  82. Volynets GP, Golub AG, Bdzhola VG, Yarmoluk SM (2007) The role of protein kinase CK2 in the regulation of oncogenesis, apoptosis and cellular stress response. Ukrainica Bioorganica Acta 5(2):25-32.
  83. Yakovenko OYa, Oliferenko AA, Golub AG, Bdzhola VG, Yarmoluk SM (2007) The new method of distribution integrals evaluations for high throughput virtual screening. Ukrainica Bioorganica Acta 5(1):52-62.
  84. Balanda AO, Volkova KD, Kovalska VB, Losytskyy MYu, Tokar VP, Prokopets VM, Yarmoluk SM (2007) Synthesis and spectral-luminescent studies of novel 4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]thieno[2,3-d]pyrimidinium styryls as fluorescent dyes for biomolecules detection. Dyes and Pigments 75(1):25-31.
  85. Volkova KD, Kovalska VB, Tatarets AL, Patsenker LD, Kryvorotenko DV, Yarmoluk SM (2007) Spectroscopic study of squaraines as protein-sensitive fluorescent dyes. Dyes and Pigments 72(3):285-292.
  86. Deligeorgiev T, Gadjev N, Vasilev A, Drexhage K-H, Yarmoluk SM (2007) Synthesis of novel monomeric and homodimeric cyanine dyes with thioacetyl substituents for nucleic acid detection. Dyes and Pigments 72(1):28–32.
  87. Shaitanov PV, Lukashov SS, Turov OV, Yarmoluk SM (2007) Synthesis and structural study of N-substituted-1,7-dithia-4-azaspiro[4.4]nonan-3-one 7,7-dioxides. Ukrainica Bioorganica Acta 5(2):56-61.
  88. Yakovenko OYa, Golub AG, Bdzhola VG, Yarmoluk SM (2006) Application of distribution function of rotation and translation degrees of freedom for CK2 inhibitors Ki estimation. Ukrainica Bioorganica Acta 4(2):47-55.
  89. Golub AG, Yakovenko OY, Bdzhola VG, Sapelkin VM, Zien P, Yarmoluk SM (2006) Evaluation of 3-Carboxy-4(1H)-quinolones as Inhibitors of Human Protein Kinase CK2. J Med Chem 49(22):6443-6450.
  90. Balanda AO, Volkova KD, Kovalska VB, Tokar VP, Yarmoluk SM (2006) Synthesis and spectral studies of styrylcyanines based on 4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]thieno[2,3-d]pyrimidinium and 5-oxo-1,2,3,5-tetrahydropyrrolo[2,1-b]quinazolinium. Ukrainica Bioorganica Acta 4(2):10-15.
  91. Kovalska VB, Tokar VP, Losytskyy MYu, Deligeorgiev T, Vassilev A, Gadjev N, Drexhage K-H, Yarmoluk SM (2006) Studies of monomeric and homodimeric oxazolo[4,5-b]pyridinium cyanine dyes as fluorescent probes for nucleic acids visualization. Journal of Biochemical and Biophysical Methods 68(3):155-165.
  92. Kovalska VB, Volkova KD, Losytskyy MYu, Tolmachev OI, Balanda AO, Yarmoluk SM (2006) 6,6'-Disubstituted benzothiazole trimethine cyanines – new fluorescent dyes for DNA detection. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 65(2):271-277.
  93. Tokar VP, Losytskyy MYu, Kovalska VB, Kryvorotenko DV, Balanda AO, Prokopets VM, Galak MP, Dmytruk IM, Yashchuk VM, Yarmoluk SM (2006) Fluorescence of styryl dyes-DNA complexes induced by single- and two-photon excitation. Journal of Fluorescence 16(6):783-791.
  94. Kostenko OM, Kovalska VB, Volkova KD, Shaytanov P, Kocheshev IO, Slominskiy YL, Pisareva IV, Yarmoluk SM (2006) New method for covalent fluorescent biomolecule labeling with hemicyanine dyeю J. Fluoresc. 16(4): 589-593.
  95. Balanda AO, Volkova KD, Kovalska VB, Losytskyy MYu, Lukashov SS, Yarmoluk SM (2006) Novel styrylcyanines and their dimers as fluorescent dyes for nucleic acids detection: synthesis and spectral-luminescent studies. Ukrainica Bioorganica Acta 4(1):17-29.
  96. Solovyov OO, Livshits LA, Kovalska VB, Losytskyy MYu, Slominski YuL, Yarmoluk SM (2006) New highly sensitive fluorescent dye Barva NA for DNA visualization after the denaturing gradient gel electrophoresis. Ukrainica Bioorganica Acta 4(1):30-33.
  97. Deligeorgiev T, Gadjev N, Vasilev A, Drexhage K-H, Yarmoluk SM (2006) Synthesis of novel monomeric cyanine dyes containing mercapto and thioacetyl substituents for nucleic acid detection. Dyes and Pigments 70(3):185-191.
  98. Kovalska VB, Losytskyy MYu, Kryvorotenko DV, Balanda AO, Tokar VP, Yarmoluk SM (2006) Synthesis of novel fluorescent styryl dyes based on the imidazo[1,2-a]pyridinium chromophore and their spectral-fluorescent properties in the presence of nucleic acids and proteins. Dyes and Pigments 68(1):39-45.
  99. Prykhod’ko AO, Yakovenko OYa, Golub AG, Bdzhola AG, Yarmoluk SM (2005) Evaluation of 4H-4-chromenone derivatives as inhibitors of protein kinase CK2. Biopolymers and cell 21(3):287–292.
  100. Sapelkin VM, Golub AG, Yakovenko OYa, Bdzhola VG, Yarmoluk SM (2005) Search for protein kinase CK2 inhibitors among 3-carboxy-4-aminoquinoline derivatives. Ukrainica Bioorganica Acta 1(1):28–32.
  101. Biver T, De Biasi A, Secco F, Venturini M, Yarmoluk S (2005) Cyanine dyes as intercalating agents: kinetic and thermodynamic studies on the DNA/Cyan40 and DNA/CCyan2 systems. Biophysical Journal (89):374-383.
  102. Chekanov MO, Synyugin АR, Lukashov SS, Yarmoluk SM. Synthesis of (1,1-dioxido-3-oxoisothiazolidin-2-yl)-benzenesulfonamides. Ukrainica Bioorganica Acta 6(1):55-60.
  103. Shaitanov PV, Bezugly YuV, Sapelkin VM, Yarmoluk SM (2006) Synthesis of 4-substituted 1-arylhexahydrothieno[3,4-b]pyrazin-2(1H)-one 6,6-dioxides. Ukrainica Bioorganica Acta 4(2):40-46.
  104. Shaitanov PV, Bezugly YuV, Charchenko VM, Lukashov SM, Yarmoluk SM (2005) Synthesis and structural characteristics of 4-(2-phenylethyl)-1,7-dithia-4-azaspiro[4.4]nonan-3-one 7,7-dioxide. Ukrainica Bioorganica Acta 3(2):39-42.
  105. Prykhodko A O, Kobzev SP, Yarmoluk SM (2005) Synthesis of 7-(3-dialkylamino-2-hydroxypropoxy)-3-aryloxychromones. Ukrainica Bioorganica Acta 1(1):33–39.
  106. Losytskyy MYu, Volkova KD, Kovalska VB, Makovenko IE, Slominskii YuL, Tolmachev OI, Yarmoluk SM (2005) Fluorescent properties of pentamethine cyanine dyes with cyclopentene and cyclohexene group in presence of biological molecules. Journal of Fluorescence 15(6):849-857.
  107. Kovalska VB, Kocheshev IO, Kryvorotenko DV, Balanda A, Yarmoluk SM (2005) Studies on the spectral-luminescent properties of the novel homodimer styryl dyes in complexes with DNA. Journal of Fluorescence 15(3):215-219.
  108. Matselyukh BP, Matselyukh DYa, Kovalska VB, Volkova KD, Kryvorotenko DV, Yarmoluk SM (2005) Studies of mutagenic activity of fluorescent DNA-sensitive monomethinecyanine and carbocyanine dyes in Ames test. Ukrainica Bioorganica Acta 3(2):27-34.
  109. Nizamov NN, Ismailov ZF, Kurtaliev EN, Nizamov ShN, Khaydarova FU, Khodjayev G, Kukharenko OP, Balanda AO, Yarmoluk SM (2005) Toxicity evaluation of the series of cyanine dyes used for nucleic acids and proteins detection. Ukrainica Bioorganica Acta 3(2):35-38.
  110. Kovalska VB, Kryvorotenko DV, Balanda AO, Losytskyy MYu, Tokar VP, Yarmoluk SM (2005) Fluorescent homodimer styrylcyanines:synthesis and spectral-luminiscent stidies in nucleic acids and protein complex. Dyes and Pigments 67(1):47-54.
  111. Prykhod’ko AO, Dubinina GG, Khilya VP, Yarmoluk SM (2004) Antiproliferative activities of some 7-hydroxy-3-aryloxy-2-trifluorometthyl-4H-4-chromenone derivatives against 60 human cancer cell lines. Biopolymers and cell 20(1–2):159–163.
  112. Kovalska VB, Losytskyy My, Yarmoluk SM (2004) Luminescence spectroscopic studies of trimethinecyanines substituted in polymethine chain with nucleic acids and proteins. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 60(1-2):129-136.
  113. Sapelkin VM, Golub AG, Yakovenko OYa, Bdzhola VG, Yarmoluk SM (2004) Search for casein kinase 2 inhibitors among 4 aminoquinazoline derivatives. Ukrainica Bioorganica Acta 1(1–2):74–79.
  114. Prykhod'ko AO, Dubinina GG, Golovach SM, Yarmoluk SM (2004) Inhibitors of protein kinase CK2. Ukrainica Bioorganica Acta 1(1–2):39–48.
  115. Wetzl BK, Yarmoluk SM, Graig DB, Wolfbeis OS (2004) Chameleon labels for staining and quantifying proteins.Angew Chem Int Ed 43:5400–5402.
  116. Dubinina GG, Golovach SM, Tarnavsky SS, Yarmoluk SM (2003) Interaction of 7-R-3-R1-7,8-dihydro-2Н,6Н-pyrrolo[3',4':4,5][1,3]thiazolo[3,2-b][1,2,4]triazine-2,6,8-triones with N-nucleophiles. Ukr Khim Zh 69(4):35-39.
  117. Lesyk RB, Zimenkovsky BS, Yarmoluk SM, Subtel’na IYu (2003) Synthesis of potential biologically active substances on the base of 5-carboxymethylidene-2,4-thiazolidinedione. Pharmaceutical journal 1:51–56.
  118. Tarnavsky SS, Dubinina GG, Golovach SM, Yarmoluk SM (2003) The relationship of antitumor activity with the structure of 3-chloro-4-(3-hydroxyanilino)-2,5-dihydropyrrole-2,5-diones. Biopolymers and Cell 19(6):548-552.
  119. Tarnavsky SS, Dubinina GG, Golovach SM, Yarmoluk SM (2003) The search of antitumor activity among derivatives of the 2,5-dihydropyrrole-2,5-dione. Biopolymers and Cell 19(3):287-291.
  120. Sapelkin VM, Ìàkovenko IE, Lukashov SS, Dubinina GG, Yarmoluk SM (2003) Antitumor activity of the 6-substituted derivatives of the 4-alkylaminoquinazolines. Biopolymers and Cell 19(5):467-472.
  121. Arkhipov VV, Prykhod'ko AO, Golub AG, Khilya VP, Yarmoluk SM (2003) Inhibitors of cyclin-dependent kinases. I. Synthesis of combinatorial libraries of 8-aminomethyl derivatives of 3-aryloxy-7-hydroxychromones and study of their antitumor activity. Biopolymers and Cell 19(2):196-201.
  122. Valyukh IV, Vyshnyak VV, Slobodyanyuk AV, Yarmoluk SM (2003) Spectroscopic study of the fluorescent dyes interaction with DNA. Functional Materials 10(3):528–533.
  123. Matselyukh BP, Yarmoluk SM, Matselyukh AB, Kovalska VB, Kocheshev IO, Kryvorotenko DV, Lukashov SS (2003) Interaction of cyanine dyes with nucleic acids: XXXI. Using of polymethine cyanine dyes for the visualization of DNA in agarose gels. Journal of Biochemical and Biophysical Methods 57(1):35-43.
  124. Yakovenko OYa, Golub AG, Losytskyy MYu, Bdzhola VG, Yarmoluk SM (2003) The mechanism of interaction of monomethine cyanine dye Cyan 40 with dsDNA: computer modelling. Biopolymers and Cell 19(1):93-98.
  125. Dubinina GG, Tarnavsky SS, Golovach SM, Yarmoluk SM (2002) Interaction of 3,4-dichloromaleimides with N- and S-nucleophiles. Ukr Khim Zh 68(8):47-51.
  126. Valyukh I, Slobodyanyuk A, Kovalska VB, Grangan A, Slominskii YL, Yarmoluk SM (2002) Spectral properties of symmetrical trimethine cyanines with a-, g- substituted polymethine chain in the presence of nucleic acids. Journal of Physical Studies 6(2):236-242.
  127. Kovalska VB, Valyukh IV, Kostenko OM, Dmitrieva SYu, Tolmachov OI, Yarmoluk SM (2002) Interaction of cyanine dyes with nucleic acids. Spectral-luminescent properties of pyrilium and pyridinium mono/trimethincyanines. Biopolymers and Cell 16(6):540-546.
  128. Yarmoluk SM, Losytskyy MYu, Kovalska VB, Tomachynski SM, Ogul'chansky TYu, Kostenko OM, Kurdyukov VV, Tolmachev OI (2002) Interaction of cyanine dyes with nucleic acids. New (pyrido)(thio)trimethincyanine dye CCyan 40 for fluorescent labeling of oligonucleotides. Biopolymers and Cell 16(4):340-346.
  129. Yarmoluk SM, Lukashov SS, Losytskyy MYu, Akerman B, Kornyushyna OS (2002) Interaction of cyanine dyes with nucleic acids: XXVI. Intercalation of the trimethine cyanine dye Cyan 2 into double-stranded DNA: study by spectral luminescence methods. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 58(14):3223-3232.
  130. Lukashov SS, Losytskyy MYu, Kovtun YuP, Yarmoluk SM (2002) Interaction of cyanine dyes with nucleic acids. Meso-substituted trimethincyanines for fluorescent detection of nucleic acids. Biopolymers and Cell 18(3):243-252.
  131. Kovalska VB, Valyukh IV, Lukashov SS, Slominskii YuL, Yarmoluk SM (2002) An investigation of tricarbocyanines "Stains-All" and "iso-Stains-All" as fluorescent nucleic acids probes. Journal of Fluorescence 12(2):209-212.
  132. Kostenko OM, Dmitrieva SY, Tolmachev OI, Yarmoluk SM (2002) New approach for fluorescent peptide labeling with pyrylium cyanine dyes. Journal of Fluorescence 12(2):173-175.
  133. Yarmoluk SM, Kovalska VB, Kocheshev IO (2002) Influence of the aggregation of homo-N-mer cyanine dyes on the nucleic acids detection sensitivity. Journal of Fluorescence 12(2):155-157.
  134. Losytskyy MYu, Yashchuk VM, Lukashov SS, Yarmoluk SM (2002) Davydov splitting in spectra of cyanine dye J-aggregates, formed on the polynucleotides. Journal of Fluorescence 12(1):109-112.
  135. Valyukh IV, Kovalska VB, Slominskii YL, Yarmoluk SM (2002) Spectroscopic studies of α,γ-disubstituted trimethine cyanine: new fluorescent dye for nucleic acids. Journal of Fluorescence 12(1):105-107.
  136. Yarmoluk SM, Losytskyy MYu, Yashchuk VM (2002) Nonradiative deactivation of the electronic excitation energy in cyanine dyes: influence of binding to DNA. Journal of Photochemistry & Photobiology, B: Biology 67(1):57-63.
  137. Yarmoluk SM, Kovalska VB, Kocheshev IO, Kachkovskiy YuYu (2002) Interaction of cyanine dyes with nucleic acids. Simulation of the aggregates structures and their electronic transitions for homo-n-mere benzothiazole cyanine dye using the quantum-mechanical methods, Current Studies of BiotechnologyV.II. – Environment:117-123.
  138. Dubinina GG, Volovenko YuM, Yarmoluk SM, Shishkina SV, Shishkin OV (2001) Reaction of N-substituted 3,4-dichloromaleimides with a-mercaptoazaheterocycles. Heterocycles 11:2189-2198.
  139. Lukashov SS, Makovenko IE, Losytskyy MYu, Slominskii YuL, Yarmoluk SM (2001) The interaction of cyanine dyes with nucleic acids. XXXIII. Meso-methylsubstituted trimethincyanines, as possible probes for fluorescent nucleic acid detection. Biopolymers and Cell 17(5):448-454.
  140. Kachkovsky GO, Lukashov SS, Yarmoluk SM, Matsuka GKh (2001) Interacion of cyanine dyes with nucleic acids. XXIII. Computer simulation of "half-intercalative" interaction of monomethyne cyanine dyes with DNA.Biopolymers and Cell 17(4):331-336.
  141. Lukashov SS, Kachkovskyy GO, Losytskyy MYu, Yarmoluk SM (2001) The interaction of cyanine dyes with nucleic acids. 22. Spectral-luminescent properties of monomethine pyrylium and pyrydinium cyanines and their DNA-complexes. Biopolymers and Cell 17(3):242-248.
  142. Ogulchansky TYu, Losytskyy MYu, Kovalska VB, Lukashov SS, Yashchuk VM, Yarmoluk SM (2001) Interaction of cyanine dyes with nucleic acids. XVIII. Formation of the carbocyanine dye J-aggregates in nucleic acid grooves. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 57(13):2705-2715.
  143. Yarmoluk SM, Kryvorotenko DV, Balanda AO, Losytskyy MY, Kovalska VB (2001) Proteins and cyanine dyes. Part III. Synthesis and spectroscopic studies of benzothiazolo-4-[1,2,6-trimethylpyridinium] monomethine cyanine dyes for fluorescent detection of bovine serum albumin in solutions. Dyes and Pigments 51(1):41-49.
  144. Lukashov SS, Losytskyy MYu, Slominskii YuL, Yarmoluk SM (2001) Interaction of cyanine dyes with nucleic acids. VII. Carbocyanine dyes, substituted in polymethine chain, as possible probes for fluorescent nucleic acid detection. Biopolymers and Cell 17(2):169-177.
  145. Yarmoluk SM, Kovalska VB, Kocheshev IA (2001) Interaction of cyanine dyes with nucleic acids. XXVII. Synthesis and spectral properties of novel homodi- and homotrimeric monomethine cyanine dyes. Dyes and Pigments 50(1):21-28.
  146. Yarmoluk SM, Lukashov SS, Ogul'chansky TYu, Losytskyy MYu, Kornyushyna OS (2001) Interaction of cyanine dyes with nucleic acids. XXI. Arguments for half-intercalation model of interaction. Biopolymers 62(4):219-227.
  147. Ogul'chansky TYu, Losytskyy MYu, Kovalska VB, Yashchuk VM, Yarmoluk SM (2001) Interactions of cyanine dyes with nucleic acids. XXIV. Aggregation of monomethine cyanine dyes in presence of DNA and its manifestation in absorption and fluorescence spectra. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 57(7):1525-1532.
  148. Yarmoluk SM, Kovalska VB, Kryvorotenko DV, Balanda AO, Ogul'chansky TYu (2001) Interaction of cyanine dyes with nucleic acids. XXV. Influence of affinity-modifying groups in the structure of benzothiazol-4-[2,6-dimethylpyridinium] dyes on the spectral properties of the dyes in the presence of nucleic acids.Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 57(7):1533-1540.
  149. Kostenko OM, Dmitrieva SU, Yarmoluk SM (2001) Peptides and cyanine dyes. 2. Covalent labelling of amino-reactive pyrilium dye for the conjugation of amino acids and peptides by means of the reaction of pyrilium cyanine dyes with amines. Biopolymers and Cell 17(1):80-84.
  150. Yarmoluk SM, Kryvorotenko DV, Kovalska VB (2001) Interaction of cyanine dyes with nucleic acids. XX. New methods for the preparation of fluorescent probes based on benzothiazol-4-[2,6-dimethylpyridinium] cyanine dyes. Dyes and Pigments 48(3):165-172.
  151. Kryvorotenko DV, Losytskyy MYu, Balanda AO, Yarmoluk SM (2000) Proteins and cyanine dyes. IV. Benzothiazol-4-[2,6-dimethylpyridinium] monomethine cyanine dyes for homogeneous detection of proteins.Vistnyk of “Lvivs'ka Politechnika” University – Chemistry 414:127-135.
  152. Ogul'chansky TYu, Yashchuk VM, Losytskyy MYu, Kocheshev IO, Yarmoluk SM (2000) Interaction of cyanine dyes with nucleic acids. XVII. Towards an aggregation of cyanine dyes in solutions as a factor facilitating nucleic acid detection. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 56(4):805-814.
  153. Losytskyy MYu, Yashchuk VM, Yarmoluk SM (2000) Electronic singlet excitations transfer in DNA-cyanine dye systemю Functional Materials 7(4):638-642.
  154. Yarmoluk SM, Kostenko AM, Dubey IY (2000) Interaction of cyanine dyes with nucleic acids. Part 19: new method for the covalent labeling of oligonucleotides with pyrylium cyanine dyes. Bioorganic and Medicinal Chemistry Letters 10(9):2201-2204.
  155. Lukashov SS, Losytskyy MYu, Yarmoluk SM, Slominskii YL (2000) The interaction of cyanine dyes with nucleic acids. ХІІ. Novel monomethyne cyanines based on the 5,6-methylenedioxy-benzothiazole and spectral-luminescent properties of their complexes with nucleic acids. Biopolymers and Cell 16(6):562-572.
  156. Ogul'chansky TYu, Yashchuk VM, Yarmoluk SM, Losytskyy My (2000) The interaction of cyanine dyes with nucleic acids. 14. Spectral peculiarities of several monomethyne benzothiazole cyanine dyes and their interaction with DNA. Biopolymers and Cell 16(5):345-355.
  157. Kryvorotenko DV, Kovalska VB, Yarmoluk SM (2000) The interaction of cyanine dyes with nucleic acids. 16. New fluorescent benzothiazole-4-[2,6-dimethylpyridinium] monomethyne cyanine dyes. Biopolymers and Cell 16(4):320-326.
  158. Yarmoluk SM (2000) Proteins and cyanine dyes. 1. Asymmetrical carbocyanine dye 14 K - a new fluorescent probe for homogeneous detection of proteins in solution. Biopolymers and Cell 16(3):236-239.
  159. Kryvorotenko DV, Kovalska VB, Yarmoluk SM (2000) Interaction of cyanine dyes with nucleic acids. 10. Synthesis and spectral properties of novel benzothiazol-4-[2,6-dimethylpyridinium] monomethyne cyanine dyes. Biopolymers and Cell 16(2):145-152.
  160. Losytskyy MYu, Kovalska VB, Yarmoluk SM (2000) Interaction of cyanine dyes with nucleic acids. 9. The study of spectral properties of cyanine dyes-DNA complexes in the presence of organic solvents. Biopolymers and Cell 16(1):75-81.
  161. Kocheshev IA, Kovalska VB, Yarmoluk SM, Akerman B, Matsuka GKh (1999) Interaction of cyanine dyes with nucleic acids. 15. Spectral-fluorescent properties of novel benzothiazolmethylene-2,5-dimethylpyridine homodi- and homotrimere cyanine dyes and their complexes with nucleic acids. Biopolymers and Cell 15(6):557-567.
  162. Kocheshev IA, Kovalska VB, Yarmoluk SM (1999) Interaction of cyanine dyes with nucleic acids. 11. Synthesis and spectral properties of novel 2,6-dimethyl-4-[(3-methyl-1,3-benzothiazol-3-ium-2-yl)methylene]-1,4-dihydro-1-pyridinium homodimer cyanine dyes. Biopolymers and Cell 15(5):449-455.
  163. Yarmoluk SM, Kovalska VB, Lukashov SS, Slominskii YL (1999) Interaction of cyanine dyes with nucleic acids. XII. β-substituted carbocyanines as possible fluorescent probes for nucleic acids detection. Bioorganic and Medicinal Chemistry Letters 9(12):1677-1678.
  164. Yarmoluk SM (1999) Interaction of cyanine dyes with nucleic acids. 8. Investigation of cyanine dyes as fluorescent probes for nucleic acids detection. Biopolymers and Cell 15(4):328-336.
  165. Yarmoluk SM, Kryvorotenko DV, Gerasymchuk YuS (1999) Interaction of cyanine dyes with nucleic acids. 6. Synthesis and spectroscopic properties of thiazole orange- amino acids conjugates. Biopolymers and Cell 15(3):247-251.
  166. Yarmoluk SM, Kovalska VB, Kovtun YuP (1999) Interaction of cyanine dyes with nucleic acids. 5. Towards model of “half intercalation” of monomethyne cyanine dyes into double-stranded nucleic acids. Biopolymers and Cell 15(1):75-82.
  167. Yarmoluk SM, Kostenko OM, Kornushyna OS, Dubey IYa (1998) Interaction of cyanine dyes with nucleic acids. 4. Efficient 5'-fluorescent labelling of oligonucleotides with monomehtyne pyrilium cyanine dye Cyan 39.Biopolymers and Cell 14(1):82–86.
  168. Yarmoluk SM, Dubey IYa (1997) Interaction of cyanine dyes with nucleic acids. 3. The use of new cyanine dyes Cyan 13 and Cyan 40 for detection of nucleic acids in agarose gel. Biopolymers and Cell 13(5):419–421.
  169. Alekseeva IV, Palchikovska LI, Shalamay AS, Tarnavsky SS, Nosach LN, Dyachenko NS (1997) The N4-aminoacid derivatives of 6-azacytidine: Syntheses and biological activity. Biopolymers and Cell 13(4):285-290.
  170. Yarmoluk SM, Kovalska VB, Smirnova TV, Shandura MP, Kovtun YuP, Matsuka GKh (1996) Interaction of cyanine dyes with nucleic acids. 2. Spectroscopic properties of methyleneoxy analogues of Thiazole Orange.Biopolymers and Cell 12(6):74-81.
  171. Yarmoluk SM, Zhyvoloup AN, Kovalska VB, Klimenko IV, Kukharenko AP, Kovtun YuP, Slominsky YuL (1996) Interaction of cyanine dyes with nucleic acids. 1. Studies on monomethyne as possible fluorescent probes for the nucleic acids. Biopolymers and Cell 12(1):69-75. 

Наші дослідження:

Інгібітори FGFR1
N-фенілнафтостирил-1-сульфонаміди Зображення
Ідентифіковано новий клас інгібіторів...



 

Інгібітори ASK1

 

Інгібітори CK2
Похідні 3-гідрокси-4'-карбоксифлавону (FLC) Зображення
З метою ідентифікувати нові інгібітори СК2...



 

Флуоресцентні Зонди

 

Молекулярний Дизайн
Молекулярний дизайн Зображення
Група молекулярного дизайну відділу...



 

© 2013 Усі права застережено
footer logo